YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition
A new study led by GCF grant recipient Jaffer Ajani of MD Anderson found a link between the cancer-associated gene YAP1 and... Read More
Long noncoding RNA SNHG16 silencing inhibits the aggressiveness of gastric cancer via upregulation of microRNA-628-3p and consequent decrease of NRP1
Scientists in China discovered that low expression of a particular MicroRNA called miR-628 is associated with lymph-node metastasis and poor prognosis in... Read More
Docetaxel, Oxaliplatin, and 5-Fluorouracil (DOF) in Metastatic and Unresectable Gastric/Gastroesophageal Junction Adenocarcinoma
A recent study in patients with metastatic gastric cancer showed that adding docetaxel to a modified FOLFOX7 chemo regimen produced a response... Read More
Safety of TAS-102 in Patients With Metastatic Gastric/GE Junction and Colorectal Cancer
Lonsurf was well tolerated and associated with no major toxicities in two trials with 850 gastric cancer patients, said Cambridge doctor Lizzy... Read More
Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer With Peritoneal Metastases
A study following 277 gastric cancer patients with peritoneal metastases found that cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy improved overall and... Read More
Taiho Oncology and Servier Present Data on LONSURF (trifluridine/tipiracil) at ASCO 2019 Gastrointestinal Cancers Symposium (ASCO GI)
A new study evaluating LONSURF in patients with previously treated metastatic gastric cancer is consistent with the overall study results published in... Read More
Taiho Oncology and Servier Announce Positive Results from LONSURF® (trifluridine/tipiracil) Study Presented at ESMO 2018 Congress and Published in The Lancet Oncology
Lonsurf receives FDA priority review for metastatic gastric cancer, with a new study presented at ESMO 2018 Congress and published in The... Read More
A Risk-Scoring Model for Predicting Lymph Node Metastasis in Early Gastric Cancer Patients: a Retrospective Study and External Validation
Scientists test a risk-scoring mode for developing lymph node metastasis that can guide and personalize treatment for patients with early gastric cancer.
Clinicopathologic features and outcomes of gastrointestinal stromal tumors arising from the esophagus and gastroesophageal junction
A small study looks into features and outcomes of gastrointestinal stromal tumors arising from the esophagus and gastroesophageal junction. They found metastatic... Read More
Taiho Oncology and Servier to Present Data on LONSURF® (trifluridine and tipiracil) and Key Investigational Compound TAS-120 at ESMO 20th World Congress on Gastrointestinal Cancer 2018
Good results from the drug Lonsurf for treating metastatic gastric cancer in a phase 3 trial are being presented this week at... Read More
