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ACCELERATING RESEARCH TOWARD A CURE
$3.8 million granted to expand research studies across the U.S.

Gastric Cancer Foundation is raising the public profile of gastric (stomach) cancer and increasing the amount of research funding and support dedicated to eradicating the disease.

The Foundation accelerates progress by funding research initiatives to better understand gastric cancer and develop improved methods of prevention, detection and treatment.

$3.8 million granted to expand research studies across the U.S.

ACCELERATING RESEARCH TOWARD A CURE

LEADING THE SEARCH FOR A CURE

GASTRIC CANCER REGISTRY

The Foundation established the first comprehensive HIPAA-compliant registry at Stanford University Medical Center to create a bridge between patients and researchers who are seeking greater understanding and more effective methods of prevention, diagnosis and treatment. Tumor, blood and saliva samples undergo whole genome sequencing and sophisticated analyses.

Patients and immediate family members who join the registry are important partners in the search for a cure.

LEARN MORE AND REGISTER


DATA AVAILABLE TO ALL RESEARCHERS

The Genome Explorer web portal – a comprehensive database of clinical and genomic information – makes data available to researchers around the globe free of charge. The Gastric Cancer Registry is on track to become the single largest repository of patient information and genomic data for stomach cancer.

PREVIEW THE NEW GENOME EXPLORER WEB PORTAL

EARLY-STAGE RESEARCH FUNDING

Grants provide early funding for investigations that have the potential to open up new possibilities for patient treatments. This type of foundation funding – seed funding at the initial stage of study — is essential in order to generate preliminary data that can be the basis for subsequently applying for larger public grants.

LEARN MORE ABOUT FOUNDATION FUNDED RESEARCH GRANTS

RESEARCH SCHOLAR AWARDS

The Ben Feinstein Memorial Research Scholar Award in Gastric Cancer provides funding and support to enable outstanding young investigators to focus their work on gastric cancer. The Foundation joined with the American Gastroenterological Association (AGA) Foundation to jointly establish this permanently endowed award which provides three-year research grants of $100,000 per year.

MEET OUR SCHOLARS

FIND CLINICAL TRIALS

Clinical trials study the effectiveness of new medicines and treatments. Participation in a clinical trial can offer an additional treatment option to patients while making an important contribution to the field, helping doctors learn more about gastric cancer and how to prevent or treat it.

It can be overwhelming to understand all the studies that are underway and how they might match with your condition. Help is available.

Our free no-obligation clinical trial matching service helps patients navigate this complex landscape to find and match with appropriate clinical trials in their area. Skilled navigators provide individualized support that prepares patients to discuss clinical study possibilities with their medical care team.

LEARN MORE AND REQUEST ASSISTANCE

Speak with a trained navigator by calling 1-855-731-6032, weekdays 8am–6pm ET

Published Research

Gastric Cancer Foundation-supported research discoveries have been published in acclaimed journals.

 

Oncogenic Fatty Acid Metabolism Rewires Energy Supply Chain in Gastric Carcinogenesis Yoonkyung Won, Bogun Jang Su-Hyung Lee, et al. GI Cancer May 2024; Volume 166, ISSUE 5, P772-786.e14
Mutational signature-based identification of DNA repair deficient gastroesophageal adenocarcinomas for therapeutic targeting Aurel Prosz, Pranshu Sahgal, Brandon M. Huffman, et al. NPJ Precis Oncol. 2024; 8: 87
Are You a TMBeliever? Mutations and Atezolizumab Response in Solid Tumors. Steven B. Maron, Samuel J. Klempner. Cancer Discov (2022) 12 (3): 602–603.
Determinants of Response and Intrinsic Resistance to PD-1 Blockade in Microsatellite Instability–High Gastric Cancer. Minsuk Kwon, Minae An, Samuel J. Klempner et al. Cancer Discov (2021) 11 (9): 2168–2185.
Aim2-mediated/IFN-β–independent regulation of gastric metaplastic lesions via CD8+ T cells. Mohamad El-Zaatari, …, Marilia Cascalho, John Y. Kao. JCI Insight 2020; 5(5):e94035.
Proliferation and Differentiation of Gastric Mucous Neck and Chief Cells During Homeostasis and Injury-induced Metaplasia Joseph Burclaff, Spencer G. Willet,1 José B. Sáenz, et al. Gastroenterology 2020 Feb;158(3):598-609.e5.
Helicobacter pylori: preying on SIVA for survival in the stomach. Sáenz JB, Mills JC. Journal of Clin Investigation 2020; 130(5):2183-2185.
Joint single cell DNA-seq and RNA-seq of gastric cancer cell lines reveals rules of in vitro evolution. Andor N, Lau BT, Catalanotti C, et al. NAR Genom Bioinform 2020; 2(2): lqaa016.
Single cell genomic characterization reveals the cellular reprogramming of the gastric tumor microenvironment. Sathe A, Grimes SM, Lau BT, Chen J, Suarez C, Huang RJ, et al. Clin Cancer Res 2020.
A Space–Time Continuum for Immunotherapy Biomarkers in Gastroesophageal Cancer? Samuel J. Klempner, Vivek Upadhyay, Joseph Chao. Clin Cancer Res (2020) 26 (24): 6401–6403.
Single-cell transcriptome analysis identifies distinct cell types and niche signaling in a primary gastric organoid model. Chen J, Lau BT, Andor N, Grimes SM, Handy C, Wood-Bouwens C, Ji HP. Sci Rep. 2019; 9(1):4536.
Acid and the basis for cellular plasticity and programming in gastric repair and cancer. Saenz and Mills. Nature Reviews Gastroenterology and Hepatology 2018; 15(5): 257-273.
Role of Dietary Metabolites in Regulating the Host Immune Response in Gastrointestinal Disease. Mohamad El-Zaatari, John Y. Kao. Frontiers in Immunology 2017; 8:51.
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