News in Gastric Cancer

News from around the world, curated by the Gastric Cancer Foundation.

Long noncoding RNA in gastric juice, plasma may be marker for gastric cancer

Changes in long noncoding RNA-AA174084 levels in the tissues, gastric juice and plasma of patients with gastric cancer were associated with clinicopathological factors, suggesting utility as a biomarker for early screening and predicting prognoses, according to research data.

To determine the diagnostic and prognostic utility of plasma and gastric juice levels of AA174084 (AA) — a long noncoding RNA (lncRNA) found with abnormal expression in gastric cancer (GC) tissues in a previous study — researchers analyzed samples from three gastroenterology centers in China from February 2011 to November 2013. Total RNA was extracted from 860 patients and controls and measured using real-time reverse transcriptase-polymerase chain reaction analysis.